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Common uses
Zocor (SIMVASTATIN) is an HMG-CoA reductase
inhibitor or "statin" used to lower bad cholesterol (LDL)
and triglyceride levels in your blood or to raise good cholesterol
(HDL) levels in adults. This medicine (Zocor - Simvastatin)
is used in combination with a low-cholesterol and low-fat
diet. Simvastatin may also be used in certain adolescent
patients, age 10 to 17 years, who have a genetically caused
cholesterol problem. This medicine (Zocor - Simvastatin)
works by blocking an enzyme that is necessary for your body
to make cholesterol. When this enzyme is blocked, your body
makes less cholesterol. Keeping your cholesterol level under
control may reduce your risk of heart problems and stroke.
This medicine (Zocor - Simvastatin) is not a cure
for high cholesterol, but may help to control it. This medicine
(Zocor - Simvastatin) may also be used to treat other
conditions as determined by your doctor.Generic Zocor
is an HMG CoA reductase inhibitor. Generic Zocor
blocks the production of cholesterol (a type of fat) in
the body. Generic Zocor is used to reduce the total amounts
of cholesterol, LDL (bad) cholesterol, triglycerides (another
type of fat), and apolipoprotein B (a protein needed to
make cholesterol) in your blood. Zocor (Zocor) is
also used to increase the level of HDL (good) cholesterol
in your blood. These actions may reduce the risk of hardening
of the arteries, which can lead to heart attacks, stroke,
and peripheral vascular disease. Generic Zocor may
also be used for purposes other than those listed in this
medication guide.
Before using
Do not take this medicine (Zocor -
Simvastatin) if you are also taking fibrates such as gemfibrozil
or fenofibrate; hiv protease inhibitors such as ritonavir,
lopinavir, nelfinavir; itraconazole; ketoconazole; macrolide
antibiotics such as erythromycin, clarithromycin, or troleandomycin;
nefazodone; or high-dose niacin (1 gram or more per day).
Additional monitoring of your dose or condition
may be needed if you are taking amiodarone, "blood thinners"
such as warfarin, bosentan, cyclosporine, dalfopristin or
quinupristin, digoxin, diltiazem, fluconazole, imatinib,
rifamycins such as rifampin, st. John's wort, verapamil,
or voriconazole.
Do not start or stop any medicine (Zocor
- Simvastatin) without doctor or pharmacist approval. Inform
your doctor of any other medical conditions including kidney
problems, muscle problems, alcohol use, allergies (especially
to other "statins"), pregnancy, or breast-feeding. Certain
medical conditions, including low blood pressure; severe
infection; uncontrolled seizures; or serious metabolic,
endocrine, or electrolyte problems may increase your risk
for side effects that can result in kidney problems. Contact
your doctor if you develop one of these conditions.
Use of this medicine (Zocor - Simvastatin)
is not recommended if you have a history of liver disease
or ongoing, abnormal liver function test results. Contact
your doctor or pharmacist if you have any questions or concerns
about taking this medicine (Zocor - Simvastatin).
Directions
Follow the directions for using this medicine
(Zocor - Simvastatin) provided by your doctor. This
medicine (Zocor - Simvastatin) may be taken on an
empty stomach or with food. If you are taking 1 dose a day,
take your dose in the evening or at bedtime as directed
by your doctor. Your dosage is based on your medical condition,
response to therapy, and the other medicine (Zocor
- Simvastatin)s that you are taking. Do not exceed the recommended
dose of this medicine (Zocor - Simvastatin).
Do not drink large amounts of grapefruit
juice (greater than 1 quart daily) or eat large amounts
of grapefruit while taking this medicine (Zocor -
Simvastatin). Store this medicine (Zocor - Simvastatin)
at room temperature, away from heat and light. For best
results, take this medicine (Zocor - Simvastatin)
regularly. Taking this medicine (Zocor - Simvastatin)
at the same time(s) each day will help you to remember.
If you miss a dose of this medicine (Zocor
- Simvastatin), take it as soon as possible. If it is almost
time for your next dose, skip the missed dose and go back
to your regular dosing schedule. Do not take 2 doses at
once.
Cautions
Do not take this medicine (Zocor -
Simvastatin) if you have had an allergic reaction to it
or are allergic to any ingredient in this product. Follow
the dietary plan provided by your doctor. It may take several
weeks for this medicine (Zocor - Simvastatin) to
work. Do not stop using this medicine (Zocor - Simvastatin)
without first checking your doctor. Keep all doctor and
laboratory appointments while you are using this medicine
(Zocor - Simvastatin). Laboratory and/or medical
tests such as blood cholesterol levels, liver function tests,
or muscle tests may be done at the start of therapy and
while you are taking this medicine (Zocor - Simvastatin)
to monitor your progress or to check for side effects.
Before you have any medical or dental treatments,
emergency care, or surgery, tell the doctor or dentist that
you are using this medicine (Zocor - Simvastatin).
This medicine (Zocor - Simvastatin) may increase
your risk for liver problems. Alcohol can also increase
this risk. Before drinking alcohol, talk with your doctor
about the safe use of this medicine (Zocor - Simvastatin)
and alcohol. This medicine (Zocor - Simvastatin)
may cause injury to your muscles especially when taken at
higher doses or when taken with certain other medicine (Zocor
- Simvastatin)s. Contact your doctor immediately if you
experience muscle pain or weakness, especially with a fever.
For women: if you are able to become pregnant,
talk with your doctor or pharmacist about the use of effective
birth control while taking this medicine (Zocor -
Simvastatin). Do not use this medicine (Zocor - Simvastatin)
if you are pregnant. If you suspect that you could be pregnant,
contact your doctor immediately. It is unknown if this medicine
(Zocor - Simvastatin) is excreted in breast milk.
Do not breast-feed while taking this medicine (Zocor
- Simvastatin).
How should I take Generic Zocor?
Take Generic Zocor exactly as directed by your doctor.
If you do not understand these directions, ask your pharmacist,
nurse, or doctor to explain them to you. Take each dose
with a full glass of water. For the greatest effect, Generic
Zocor is usually taken at bedtime or with an evening
meal. Follow your doctor's instructions. Your doctor may
want to monitor your liver function with blood tests before
starting treatment with Generic Zocor and every six
months after both the start of your treatment and any increase
in dose. Depending on the results of these tests, your doctor
can determine how much monitoring you will require. Grapefruit
and grapefruit juice may interact with Generic Zocor.
The interaction could lead to potentially dangerous effects.
Discuss the use of grapefruit and grapefruit juice with
your doctor. Do not increase or decrease the amount of grapefruit
products in your diet without first talking to your doctor.
Eat a low-fat, low-cholesterol diet. To realize beneficial
effects from Generic Zocor, avoid fatty, high-cholesterol
foods. It is important to take Generic Zocor regularly to
get the most benefit. Do not stop taking Generic Zocor
without first talking to your doctor. Generic Zocor may
need to be taken on a long-term basis for the treatment
of high cholesterol. Your doctor may want you to have blood
tests or other medical evaluations during treatment with
Generic Zocor to monitor progress and side effects.
Store Generic Zocor at room temperature away from
moisture and heat.
Possible side effects
Side effects that may occur while taking
this medicine (Zocor - Simvastatin) include constipation,
diarrhea, or stomach upset. If they continue or are bothersome,
check with your doctor. Contact your doctor immediately
if you experience muscle aches, pain, tenderness, or weakness,
especially if associated with unusual tiredness and a fever;
yellowing of skin or eyes; dark urine; change in the amount
of urine; stomach pain; ongoing nausea or vomiting; blurred
vision; or unusual bleeding or bruising.
An allergic reaction to this medicine (Zocor
- Simvastatin) is unlikely, but seek immediate medical attention
if it occurs. Symptoms of an allergic reaction include rash,
itching, swelling, dizziness, or trouble breathing. If you
notice other effects not listed above, contact your doctor,
nurse, or pharmacist.
If you take too much
If overdose is suspected, contact your local
poison control center or emergency room immediately.
Additional information
For best results, this medicine (Zocor
- Simvastatin) should be used along with exercise, a low-cholesterol/low-fat
diet, and a weight loss program if you are overweight. Follow
the dietary plan provided by your doctor. Consult with your
doctor. Do not share this medicine (Zocor - Simvastatin)
with others for whom it was not prescribed. Do not use this
medicine (Zocor - Simvastatin) for other health conditions.
Keep this medicine (Zocor - Simvastatin) out of the
reach of children and pets. If using this medicine (Zocor
- Simvastatin) for an extended period of time, obtain refills
before your supply runs out.
Drug interactions
Drug interactions can result in unwanted
side effects or prevent a medicine (Zocor - Simvastatin)
from doing its job. Some medicine (Zocor - Simvastatin)s
or medical conditions may interact with this medicine (Zocor
- Simvastatin). Inform your doctor or pharmacist of all
prescription and over-the-counter medicine (Zocor
- Simvastatin) that you are taking.Do not take Generic Zocor
without first talking to your doctor if you are taking any
of the following medicines: cyclosporine (Sandimmune, Neoral);
gemfibrozil (Lopid), clofibrate (Atromid-S), or fenofibrate
(Tricor); niacin (Nicolar, Nicobid, Slo-Niacin, others);
erythromycin (E-Mycin, E.E.S., Ery-Tab, others) or clarithromycin
(Biaxin); cholestyramine (Questran) or colestipol (Colestid);
an antifungal medication such as itraconazole (Sporanox),
fluconazole (Diflucan), or ketoconazole (Nizoral); nefazodone
(Serzone); digoxin (Lanoxin, Lanoxicaps); warfarin (Coumadin);
a protease inhibitor such as amprenavir (Agenerase), indinavir
(Crixivan), nelfinavir (Viracept), ritonavir (Norvir), lopinavir-ritonavir
(Kaletra), or saquinavir (Invirase, Fortovase); amiodarone
(Cordarone, Pacer one); or verapamil (Calan, Covera-HS,
Isoptin, Verelan). You may not be able to take Zocor,
or you may require a dosage adjustment or special monitoring
during treatment if you are taking any of the medicines
listed above. Drugs other than those listed here may also
interact with Generic Zocor. Talk to your doctor
and pharmacist before taking any prescription or over-the-counter
medicines, including vitamins, minerals, and herbal products.
Zocor is an Cholesterol medicine in
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