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This is an anti-diabetic medicine (Glucotrol
XL - Glipizide XL) (sulfonylurea-type) used along with
a proper diet and exercise program to control high blood
sugar. It is used in patients with type 2 diabetes (non-insulin-dependent
diabetes). It works by stimulating the release of your body's
natural insulin. Effectively controlling blood sugar helps
prevent heart disease, strokes, kidney disease, blindness,
and circulation problems, as well as sexual function problems
(impotence).Glucotrol XL is in a class of drugs called
sulfonylureas. It is used to help control blood sugar levels.
Glucotrol XL is used to treat noninsulin-dependent (Type
II) diabetes mellitus (NIDDM) along with diet, exercise,
and insulin therapy, if necessary.
Before using
Additional monitoring of your dose or condition
may be needed if you are taking other diabetes medicine
(Glucotrol XL - Glipizide XL)s (e.g., insulin, metformin),
aspirin or aspirin-like medicine (Glucotrol XL -
Glipizide XL)s (e.g., salicylates, nsaids such as ibuprofen,
phenylbutazone), azole antifungals (e.g., fluconazole),
beta-blockers including glaucoma eye drops (e.g., propranolol,
timolol, metoprolol), birth control pills, "blood thinners"
(e.g., warfarin), calcium channel blockers (e.g., diltiazem),
chloramphenicol, cimetidine, clofibrate, corticosteroids
(e.g., prednisone), decongestants (e.g., pseudoephedrine),
diazoxide, diet pills, epinephrine, estrogens, isoniazid,
mao inhibitors (e.g., furazolidone, linezolid, moclobemide,
phenelzine, procarbazine, selegiline, isocarboxazid, tranylcypromine),
niacin, phenothiazines (e.g., promethazine), phenytoin,
probenecid, quinolone antibiotics (e.g., ciprofloxacin),
rifampin, sulfonamides (e.g., sulfa antibiotics), thyroid
medicine (Glucotrol XL - Glipizide XL)s, "water pills"
(diuretics such as hydrochlorothiazide, furosemide), fenugreek,
or ginseng.
Do not start or stop any medicine (Glucotrol
XL - Glipizide XL) without doctor or pharmacist approval.
Inform your doctor of any other medical conditions including
liver, kidney, or thyroid disease; certain hormonal conditions
(adrenal/pituitary insufficiency, siadh-syndrome of inappropriate
secretion of antidiuretic hormone), electrolyte imbalance
(hyponatremia), high blood pressure, allergies, pregnancy,
or breast-feeding. Use of this medicine (Glucotrol XL
- Glipizide XL) is not recommended if you have metabolic
conditions (e.g., diabetic ketoacidosis). Contact your doctor
or pharmacist if you have any questions or concerns about
taking this medicine (Glucotrol XL - Glipizide XL).
Glucotrol XL Precautions
Tell you doctor if you have kidney disease, have liver
disease, have thyroid disease, have type 1 diabetes, have
a serious infection, illness, or injury, or need surgery.
Glucotrol XL should not be used without first talking
to your doctor if you are pregnant or are planning a pregnancy.
As it might passes into breast milk and may affect a nursing
infant. Caution is advised when this product is used in
the elderly since this group may be more sensitive to side
effects. Follow diet, medication, and exercise routines
closely. Changing any of these things can effect blood sugar
levels. Avoid alcohol. It lowers blood sugar and may interfere
with your diabetes treatment. Tell your doctor and dentist
that you are taking this medication before you undergo any
surgery.
Directions
Follow the directions for using this medicine
(Glucotrol XL - Glipizide XL) provided by your doctor.
Take this medicine (Glucotrol XL - Glipizide XL)
by mouth 30 minutes before a meal. The dosage is based on
your medical condition and response to therapy. Take this
medicine (Glucotrol XL - Glipizide XL) regularly
to receive the most benefit from it. Taking the medicine
(Glucotrol XL - Glipizide XL) at the same time each
day will help you to remember. Monitor blood glucose levels
on a regular basis. Store this medicine (Glucotrol XL
- Glipizide XL) in a tightly-closed container at room temperature
below 86 degrees f (30 degrees c), away from heat, moisture,
and light. If you miss a dose of this medicine (Glucotrol
XL - Glipizide XL), take it as soon as possible. If
it is almost time for your next dose, skip the missed dose
and go back to your regular dosing schedule. Do not take
2 doses at once.
Cautions
It is important that you keep all doctor
and laboratory appointments while you are using this medicine
(Glucotrol XL - Glipizide XL). Laboratory and/or
medical tests (e.g., liver and kidney function tests, fasting
blood glucose, glycosylated hemoglobin, complete blood counts)
should be performed periodically to monitor your progress
or check for side effects. Regularly check your blood or
urine for sugar as directed by your doctor or pharmacist.
You may experience blurred vision, dizziness,
or drowsiness due to extremely low or high blood sugar levels.
Use caution engaging in activities requiring alertness such
as driving or operating machinery. Limit alcoholic beverages
while using this medicine (Glucotrol XL - Glipizide
XL) because they can increase the risk of developing hypoglycemia.
Rarely, alcohol can interact with glipizide and cause a
serious reaction (disulfiram-like reaction) with symptoms
such as facial flushing, nausea, vomiting, dizziness, or
stomach pain. Consult your doctor or pharmacist about the
safe use of alcohol. During times of stress, such as fever,
infection, injury, or surgery, it may be more difficult
to control your blood sugar. Consult your doctor, as a change
in your medicine (Glucotrol XL - Glipizide XL) may
be required.
This medicine (Glucotrol XL - Glipizide
XL) may cause increased sensitivity to the sun. Avoid exposure
to the sun or sunlamps until you know how you react to this
medicine (Glucotrol XL - Glipizide XL). Use a sunscreen
or protective clothing if you must be outside for a prolonged
period. Before you begin taking any new medicine (Glucotrol
XL - Glipizide XL), either prescription or over-the-counter,
check with your doctor or pharmacist. Caution is advised
when using this medicine (Glucotrol XL - Glipizide
XL) in the elderly since they may be more sensitive to the
effects of this medicine (Glucotrol XL - Glipizide
XL), especially hypoglycemia.
For women: if you plan on becoming
pregnant, discuss with your doctor the benefits and risks
of using this medicine (Glucotrol XL - Glipizide
XL) during pregnancy. Glipizide is not recommended for use
for at least 1 month before delivery due to the potential
for fetal harm. Insulin may be preferred during pregnancy.
Discuss all options with your doctor. It is unknown if this
medicine (Glucotrol XL - Glipizide XL) is excreted
in breast milk. Do not breast-feed while taking this medicine
(Glucotrol XL - Glipizide XL).
Possible side effects
Side effects, that may go away during treatment,
include nausea, vomiting, loss of appetite, diarrhea, constipation,
upset stomach, headache, or weight gain. If they continue
or are bothersome, check with your doctor. Contact your
doctor immediately if you experience persistent sore throat
or fever, easy bleeding/bruising, stomach pain, yellowing
eyes or skin, dark urine, unusual tiredness or weakness,
unusual or sudden weight gain, mental/mood changes, swelling
of the hands or feet, or seizures.
This medicine (Glucotrol XL - Glipizide
XL) can cause low blood sugar (hypoglycemia). This effect
may occur if you do not consume enough calories (from food,
juices, fruit, etc). The symptoms include chills, cold sweat,
blurred vision, dizziness, drowsiness, shaking, rapid heart
rate, weakness, headache, fainting, tingling of the hands
or feet, or hunger. It is a good habit to carry glucose
tablets or gel to treat low blood sugar. If you are in a
situation where you do not have these reliable forms of
glucose, eat a quick source of sugar such as table sugar,
honey, or candy, or drink a glass of orange juice or non-diet
soda to quickly raise your blood sugar level. Tell your
doctor immediately about the reaction.
To prevent hypoglycemia, eat meals on a regular
schedule and do not skip meals. Symptoms of high blood sugar
(hyperglycemia) include thirst, increased urination, confusion,
drowsiness, flushing, rapid breathing, or fruity breath
odor. If these symptoms occur, tell your doctor immediately.
Your medicine (Glucotrol XL - Glipizide XL) dosage
may need to be increased. An allergic reaction to this medicine
(Glucotrol XL - Glipizide XL) is unlikely, but seek
immediate medical attention if it occurs. Symptoms of an
allergic reaction include rash, itching, swelling, dizziness,
or trouble breathing. If you notice other effects not listed
above, contact your doctor, nurse, or pharmacist.
If you take too much
If overdose is suspected, contact your local
poison control center or emergency room immediately. Symptoms
of overdose may include shakiness, rapid heartbeat, sweating,
and loss of consciousness.
Additional information
Carry an identification card at all times
that says you are taking this medicine (Glucotrol XL
- Glipizide XL). Proper diet, regular exercise, and regular
testing of blood sugar are important for best results when
using this medicine (Glucotrol XL - Glipizide XL).
This medicine (Glucotrol XL - Glipizide XL) is not
a substitute for them. Be sure to follow the diet plan provided
by your doctor. It is recommended that you attend a diabetes
education program to better understand diabetes, prevention
of complications, and all the important aspects of its treatment.
These include meals/diet, exercise, weight loss, personal
hygiene, medicine (Glucotrol XL - Glipizide XL)s
and blood glucose monitoring, and the need for regular eye,
foot, and medical exams. Follow your doctor's instructions
carefully.
Do not share this medicine (Glucotrol
XL - Glipizide XL) with others for whom it was not prescribed.
Do not use this medicine (Glucotrol XL - Glipizide
XL) for other health conditions. Keep this medicine (Glucotrol
XL - Glipizide XL) out of the reach of children and
pets. If using this medicine (Glucotrol XL - Glipizide
XL) for an extended period of time, obtain refills before
your supply runs out.
Drug interactions
Drug interactions can result in unwanted
side effects or prevent a medicine (Glucotrol XL
- Glipizide XL) from doing its job. Some medicine (Glucotrol
XL - Glipizide XL)s or medical conditions may interact
with this medicine (Glucotrol XL - Glipizide XL).
Inform your doctor or pharmacist of all prescription and
over-the-counter medicine (Glucotrol XL - Glipizide
XL) that you are taking.Tell your doctor of all nonprescription
and prescription medication you are using, especially :
aspirin or another salicylate such as magnesium/ choline
salicylate (Trilisate), salsalate (Disalcid, others), choline
salicylate (Arthropan), magnesium salicylate (Magan), or
bismuth subsalicylate (Pepto-Bismol), a nonsteroidal anti-inflammatory
drug (NSAID) such as ibuprofen (Motrin, Advil, Nuprin, others),
ketoprofen (Orudis, Orudis KT, Oruvail), diclofenac (Voltaren,
Cataflam), etodolac (Lodine), indomethacin (Indocin), nabumetone
(Relafen), oxaprozin (Daypro), naproxen (Anaprox, Naprosyn,
Aleve), and others, a sulfa-based drug such as sulfamethoxazole-trimethoprim
(Bactrim, Septra), sulfisoxazole (Gantrisin), or sulfasalazine
(Azulfidine), a monoamine oxidase inhibitor (MAOI) such
as isocarboxazid (Marplan), tranylcypromine (Parnate), or
phenelzine (Nardil), a beta-blocker such as propranolol
(Inderal), atenolol (Tenormin), acebutolol (Sectral), metoprolol
(Lopressor), and others, a diuretic (water pill) such as
hydrochlorothiazide (HCTZ, Hydrodiuril), chlorothiazide
(Diuril), and others, a steroid medicine such as prednisone
(Deltasone, Orasone, others), methylprednisolone (Medrol,
others), prednisolone (Prelone, Pediapred, others), and
others, a phenothiazine such as chlorpromazine (Thorazine),
fluphenazine (Prolixin, Permitil), prochlorperazine (Compazine),
promethazine (Phenergan), and others, phenytoin (Dilantin),
isoniazid (Nydrazid), or prescription, over-the-counter,
or herbal cough, cold, allergy, or weight loss medications.
Drugs other than those listed here may also interact with
Glucotrol XL.
Talk to your doctor and pharmacist before taking any prescription
or over-the-counter medicines.
Glucotrol XL is an Diabetes medicine
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